KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC27
All Species:
36.06
Human Site:
Y539
Identified Species:
66.11
UniProt:
P30260
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30260
NP_001107563.1
824
91867
Y539
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Chimpanzee
Pan troglodytes
XP_511624
824
91839
Y539
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Rhesus Macaque
Macaca mulatta
XP_001115994
824
91959
Y539
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Dog
Lupus familis
XP_548047
825
91842
Y540
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Cat
Felis silvestris
Mouse
Mus musculus
NP_663411
825
91824
Y540
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Rat
Rattus norvegicus
NP_001019964
824
91645
Y539
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520967
385
43892
E129
L
S
E
Y
M
Q
A
E
R
I
F
S
E
V
R
Chicken
Gallus gallus
NP_001006331
833
92606
Y540
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Frog
Xenopus laevis
NP_001085568
833
92363
Y540
R
V
E
G
M
E
I
Y
S
T
T
L
W
H
L
Zebra Danio
Brachydanio rerio
NP_958857
790
87878
V534
N
S
P
E
P
W
C
V
V
G
N
C
F
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648093
900
101266
Y617
R
L
D
Y
M
E
I
Y
S
S
S
L
W
H
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786824
824
91473
L533
Y
S
T
T
L
W
H
L
Q
K
E
T
A
L
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38042
758
85418
Q502
F
N
R
L
K
D
L
Q
P
A
R
V
K
D
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
96.3
99.1
N.A.
96.9
97.4
N.A.
43.6
94.5
89.6
76.5
N.A.
39.2
N.A.
N.A.
49.2
Protein Similarity:
100
99.8
97.2
99.2
N.A.
98.6
98.5
N.A.
45.2
96.6
94.5
84.3
N.A.
57.4
N.A.
N.A.
67.2
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
13.3
100
100
6.6
N.A.
66.6
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
100
100
13.3
N.A.
93.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
0
0
0
0
8
0
0
0
% C
% Asp:
0
0
8
0
0
8
0
0
0
0
0
0
0
8
0
% D
% Glu:
0
0
70
8
0
70
0
8
0
0
8
0
8
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
8
0
8
0
0
% F
% Gly:
0
0
0
62
0
0
0
0
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
70
0
% H
% Ile:
0
0
0
0
0
0
70
0
0
8
0
0
0
0
0
% I
% Lys:
0
0
0
0
8
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
8
8
0
8
8
0
8
8
0
0
0
70
0
8
77
% L
% Met:
0
0
0
0
77
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
8
0
8
0
0
0
8
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
8
0
8
8
0
0
0
0
0
0
% Q
% Arg:
70
0
8
0
0
0
0
0
8
0
8
0
0
0
8
% R
% Ser:
0
24
0
0
0
0
0
0
70
8
8
8
0
8
8
% S
% Thr:
0
0
8
8
0
0
0
0
0
62
62
8
0
0
0
% T
% Val:
0
62
0
0
0
0
0
8
8
0
0
8
0
8
0
% V
% Trp:
0
0
0
0
0
16
0
0
0
0
0
0
70
0
0
% W
% Tyr:
8
0
0
16
0
0
0
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _